I’m saying: take two groups of people, both of which haven’t ever done psychedelics, and both of which have a condition for which psychedelics don’t produce a response by themselves (improvement in symptoms; perhaps hypertension). Give one group psychedelics, and then wait a few weeks (for it to clear out of their system). Then, give 1/3 of each group sham pills, 1/3 in each group real medicine, and 1/3 in each group no pills at all. Measure the responses.
Psychedelics either have an influence on the placebeo effect (for a specific condition like hypertension), or they don’t. Can you suggest a better way of determining which is the case?